Human Physiology MCQs (Set-1)

Difficulty: Mixed

What does physiology study?

A Body structures alone
B Disease classifications only
C Patient treatment plans
D How body parts function

Why does the body maintain homeostasis?

A Make values exactly constant
B Keep internal conditions within ranges
C Prevent system interactions
D Stop all internal changes

What is a physiological set point?

A A patient treatment goal
B A fixed organ location
C Reference value for regulation
D A maximum heart rate

Why can a homeostatic variable change slightly?

A Normal ranges allow fluctuation
B Regulation never operates
C Organs stop communicating
D Every change is harmful

What does a sensor do in a feedback loop?

A Produces the final response
B Stores the set point
C Compares values with a range
D Detects a physiological change

How does a control center guide regulation?

A Creates the initial stimulus
B Compares input with a range
C Detects every external sound
D Carries hormones to tissues

Which component carries out the response?

A Sensor
B Set point
C Effector
D Stimulus

What is the usual effect of negative feedback?

A Reverses the initial deviation
B Stops all receptor signals
C Creates a new set point
D Amplifies the deviation

How does positive feedback affect a change?

A Blocks all effectors
B Reverses it immediately
C Keeps it exactly constant
D Reinforces it until an endpoint

Which process is a common positive feedback example?

A Routine temperature control
B Childbirth contractions
C Blood glucose regulation
D Water balance regulation

When body temperature rises, which response helps lower it?

A Reduced skin blood flow
B Increased muscle tone
C Sweating
D Shivering

What does shivering help the body do?

A Generate heat through muscle activity
B Reduce blood glucose
C Increase heat loss
D Lower metabolic activity

When blood glucose rises, which hormone helps lower it?

A Glucagon
B Thyroxine
C Melatonin
D Insulin

Which hormone raises blood glucose when levels fall?

A Oxytocin
B Glucagon
C Aldosterone
D Insulin

How do most endocrine hormones reach target tissues?

A Across synapses only
B Along bone surfaces
C Through the bloodstream
D Through airways

What must a target cell have to respond to a hormone?

A A matching receptor
B A second nucleus
C A motor neuron
D A blood vessel

Which sequence best represents a homeostatic loop?

A Hormone, organ, tissue, set point
B Sensor, organ, stimulus, cell
C Effector, tissue, organ, stimulus
D Stimulus, sensor, control center, effector

What does a negative-feedback response aim to restore?

A A permanent increase
B Regulated variable’s normal range
C A new organ system
D The original stimulus strength

Which transport moves particles down a concentration gradient without ATP?

A Active transport
B Endocytosis
C Passive transport
D Protein synthesis

What is diffusion?

A Net movement down a gradient
B Transport against a gradient
C Vesicle release outside cells
D Water movement using ATP

Which substance moves during osmosis?

A Ions through a synapse
B Protein against a gradient
C Oxygen using a pump
D Water across a membrane

Why does active transport require energy?

A It always moves water
B It can move substances uphill
C It occurs only outside cells
D It needs no membrane proteins

What does the sodium-potassium pump move?

A Calcium out, glucose in
B Water out, oxygen in
C Sodium out, potassium in
D Potassium out, sodium in

Which membrane feature helps control what enters a cell?

A Selective permeability
B Permanent pore size
C Rigid mineral coating
D Open passage for everything

What is ATP’s main role in cellular physiology?

A Store genetic instructions
B Carry oxygen in blood
C Form tissue membranes
D Provide usable cellular energy

When does a neuron typically initiate an action potential?

A When the membrane is destroyed
B When threshold is reached
C Only during sleep
D Whenever a hormone binds

Where does an action potential travel in a neuron?

A Inside a hormone gland
B Across a blood vessel
C Along the axon
D Through the nucleus only

What crosses a chemical synapse to signal another cell?

A Neurotransmitter
B Hemoglobin
C Insulin only
D Cerebrospinal fluid

How can a neurotransmitter affect a target neuron?

A Replace its membrane
B Carry oxygen to it
C Enter its nucleus directly
D Bind to its receptor

Which structure receives many incoming signals on a neuron?

A Node of Ranvier
B Dendrites
C Axon terminals
D Myelin sheath

Where does external respiration occur?

A Inside body tissues
B Within the stomach
C At the lung alveoli
D In kidney tubules

Which gases cross the respiratory membrane?

A Oxygen and carbon dioxide
B Water and sodium
C Insulin and oxygen
D Nitrogen and glucose

Where does oxygen move during external respiration?

A Blood into stomach
B Blood into alveoli
C Tissues into alveoli
D Alveoli into blood

What is internal respiration?

A Air movement into lungs
B Gas exchange at body tissues
C Gas exchange in alveoli
D Oxygen transport by hemoglobin

Why do respiratory gases diffuse across membranes?

A Muscle contraction only
B Hormone receptors
C Partial-pressure gradients
D ATP-powered pumps

Which blood component carries most oxygen?

A Hemoglobin in red cells
B Glucose in plasma
C Platelets in plasma
D Albumin in white cells

What is pulmonary ventilation?

A Blood movement through lungs
B Gas exchange at tissues
C Food movement through gut
D Air movement into and out

What does perfusion describe in the lungs?

A Food flow through stomach
B Blood flow through capillaries
C Hormone flow through glands
D Airflow through bronchi

Why is carbon dioxide removed from the body?

A It forms the cell membrane
B Main blood protein
C It is cellular metabolism waste
D It is blood’s main protein

Which organ system adjusts water loss by changing urine concentration?

A Urinary system
B Integumentary system
C Skeletal system
D Digestive system

What does antidiuretic hormone promote in the kidneys?

A Calcium loss in sweat
B Protein digestion
C Glucose release into urine
D Water reabsorption

What can rising blood solute concentration trigger?

A Increased bone growth
B Thirst
C Reduced water seeking
D Lower breathing rate

How do kidneys help maintain homeostasis?

A Exchange gases with air
B Produce nerve impulses
C Regulate water and wastes
D Digest dietary proteins

Which control pattern commonly regulates hormone secretion?

A Negative feedback
B Positive feedback only
C No receptor involvement
D Random signaling

Why can one hormone cause different effects in different tissues?

A All cells have identical receptors
B Blood moves in one direction
C Hormones change their own structure
D Target cells differ in response

What is downregulation in hormone signaling?

A More hormone release
B Fewer target-cell receptors
C Faster nerve conduction
D Increased blood flow

How does the body respond when a feedback loop reaches its set point?

A The sensor stops existing
B The organ permanently changes
C Effector response decreases
D The stimulus always grows

What distinguishes a positive-feedback loop from negative feedback?

A It intensifies the original change
B It works without stimuli
C It reverses any change
D It cannot use effectors

Why can ventilation and perfusion both affect gas exchange?

A Hormones must bind first
B Food must be digested
C Bones must release calcium
D Air and blood must meet

What is a likely result when oxygen diffuses into pulmonary blood?

A The lungs stop ventilating
B Blood oxygenation increases
C The heart stops pumping
D Carbon dioxide production stops